what is the actual free energy chang?
If the isomerization reaction in the glycolytic pathway catalyzed by phosphoglucoisomerase:
glucose 6-phosphate --> fructose 6-phosphate
has a standard free energy change of +0.4 kcal/mol at 25˚C,
then  what is the actual free energy change (in kcal/mole) at 25˚C when:
the concentration of glucose-6-phosphate is 20 microMolar (20 x 10-6 M) and
the concentration of fructose 6-phosphate is 5 microMolar (5 x 10-6 M)?
 Is the reaction favorable or not?
Show how you arrived at your answers if you want to receive partial credit. Note that numbers above are in units of kilocalories, not kilojoules. R = 1.98 x 10-3 kcal K-1 mol-1
- hcbiochemLv 73 weeks ago
Why is your prof still using kcal instead of kJ??????
(Sorry...a small pet peeve of mine.)
∆G = ∆Go + RT ln [F-6-P]/[G-6-P]
∆G = 0.4 kcal/mol + (1.98X10^-3)(298K) ln (5X10^-6 / 20X10^-6) = -0.4 kcal/mol